Background:

This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Applications:

ELISA, WB, IHC

Name of antibody:

GTF2I

Immunogen:

Synthetic peptide of human GTF2I

Full name:

general transcription factor IIi

Synonyms：

WBS; DIWS; SPIN; IB291; BAP135; BTKAP1; TFII-I; WBSCR6; GTFII-I

SwissProt:

P78347

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

112 kDa

WB Positive control:

HepG2 cells

WB Recommended dilution:

200-1000