Background:

Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

Applications:

ELISA, WB, IHC

Name of antibody:

GTF3C4

Immunogen:

Synthetic peptide of human GTF3C4

Full name:

general transcription factor IIIC subunit 4

Synonyms:

KAT12; TFIII90; TFIIIC90; TFIIIC290; TF3C-delta; TFIIICDELTA

SwissProt:

Q9UKN8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

150-300

WB Predicted band size:

92 kDa

WB Positive control:

A172, Hela, Jurkat and Raji cell lysates

WB Recommended dilution:

1000-5000