Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Applications:

ELISA, WB, IHC

Name of antibody:

H2BC1

Immunogen:

Synthetic peptide of human H2BC1

Full name:

H2B clustered histone 1

Synonyms:

STBP; TH2B; H2BFU; TSH2B; hTSH2B; TSH2B.1; HIST1H2BA; bA317E16.3

SwissProt:

Q96A08

IHC positive control:

Human esophagus cancer and Human liver cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

14 kDa

WB Positive control:

TM4, A549 and PC-3 cell, Human prostate tissue and Mouse adipose tissue lysates

WB Recommended dilution:

200-1000