Background:

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later,  hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'.

Applications:

ELISA, WB, IHC

Name of antibody:

HBE1

Immunogen:

Fusion protein of human HBE1

Full name:

hemoglobin subunit epsilon 1

Synonyms:

HBE

SwissProt:

P02100

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

30-150

WB Predicted band size:

16 kDa

WB Positive control:

Human placenta tissue lysate

WB Recommended dilution:

500-2000