Background:

This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011]

Applications:

WB

Name of antibody:

PXN(Phospho-Ser178)

Immunogen:

Peptide sequence around phosphorylation site of Serine 178(A-L-S(p)-P-L) derived from Human Paxillin.

Full name:

paxillin

Synonyms：

PXN

SwissProt:

P49023

WB Predicted band size:

65 kDa

WB Positive control:

HT29 cells lysates

WB Recommended dilution:

500-1000