Background:

The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation.

Applications:

WB

Name of antibody:

RACGAP1(Phospho-Ser387)

Immunogen:

Peptide sequence around phosphorylation site of serine 387 (R-I-S(p)-G-C) derived from Human GTPase Activating Protein.

Full name:

Rac GTPase activating protein 1

Synonyms：

CYK4; ID-GAP; HsCYK-4; MgcRacGAP

SwissProt:

Q9H0H5

WB Predicted band size:

71 kDa

WB Positive control:

COS7 cells lysates

WB Recommended dilution:

500-1000