Background:

RBM38 is a cell cycle protein found in the cytosol and the nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3’-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain.

Applications:

ELISA, IHC

Name of antibody:

RBM38

Immunogen:

Synthetic peptide of human RBM38

Full name:

RNA binding motif protein 38

Synonyms：

RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2

SwissProt:

Q9H0Z9

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human esophagus cancer and Human liver cancer

IHC Recommend dilution:

50-300