Background:

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.

Applications:

ELISA, WB

Name of antibody:

TNNC1

Immunogen:

Full length fusion protein

Full name:

troponin C type 1 (slow)

Synonyms：

TNC; TN-C; TNNC; CMD1Z; CMH13

SwissProt:

P63316

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

18 kDa

WB Positive control:

Mouse skeletal muscle tissue

WB Recommended dilution:

500-2000