Background:

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

TP53BP2

Immunogen:

Synthetic peptide of human TP53BP2

Full name:

tumor protein p53 binding protein, 2

Synonyms：

BBP, 53BP2, ASPP2, P53BP2, PPP1R13A

SwissProt:

Q13625

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human colon cancer and Human gastric cancer

IHC Recommend dilution:

10-50