Background:

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

Applications:

ELISA, IHC

Name of antibody:

MAGEB2

Immunogen:

Synthetic peptide of human MAGEB2

Full name:

melanoma antigen family B, 2

Synonyms：

DAM6; CT3.2; MAGE-XP-2

SwissProt:

O15479

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100