Full name:

methylthioadenosine phosphorylase

Synonyms:

BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249

Swissprot:

Q13126

Gene Accession:

BC018625

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.