Background:

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.

Applications:

WB

Name of antibody:

GTF2IRD1

Immunogen:

Synthesized peptide derived from N-terminal of human GTF2IRD1.

Full name:

GTF2I repeat domain containing 1

Synonyms：

BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1

SwissProt:

Q9UHL9

WB Predicted band size:

106 kDa

WB Positive control:

293 cells lysate

WB Recommended dilution:

500-3000