Background:

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

GYPC

Immunogen:

Fusion protein of human GYPC

Full name:

glycophorin C

Synonyms：

GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2

SwissProt:

P04921

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human colon cancer and Human tonsil

IHC Recommend dilution:

100-300