Background:

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]

Applications:

ELISA, WB, IHC

Name of antibody:

GZMH

Immunogen:

Synthetic peptide of human GZMH

Full name:

granzyme H

Synonyms:

CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2

SwissProt:

P20718

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

27 kDa

WB Positive control:

Hela and 231 cell lysates

WB Recommended dilution:

1000-5000