Background:

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

GZMM

Immunogen:

Synthetic peptide of human GZMM

Full name:

granzyme M (lymphocyte met-ase 1)

Synonyms：

MET1; LMET1

SwissProt:

P51124

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

20-100