Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]

Applications:

ELISA, IHC

Name of antibody:

H2BC11

Immunogen:

Synthetic peptide of human H2BC11

Full name:

H2B clustered histone 11

Synonyms:

H2BJ; H2B/r; H2BFR; HIST1H2BJ

SwissProt:

P06899

IHC positive control:

Human thyroid cancer and Human tonsil

IHC Recommend dilution:

25-100