Background:

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5.

Applications:

WB

Name of antibody:

HAT1

Immunogen:

Synthesized peptide derived from Internal of human HAT.

Full name:

histone acetyltransferase 1

Synonyms：

KAT1

SwissProt:

O14929

WB Predicted band size:

50 kDa

WB Positive control:

K562 cell lysate

WB Recommended dilution:

500-3000