Background:

Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.

Applications:

ELISA, WB, IHC

Name of antibody:

PTX3

Immunogen:

Synthetic peptide of human PTX3

Full name:

pentraxin 3, long

Synonyms：

TSG-14; TNFAIP5

SwissProt:

P26022

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human brain

IHC Recommend dilution:

10-50

WB Predicted band size:

42 kDa

WB Positive control:

Hepg2 cells

WB Recommended dilution:

500-2000