Background:

This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

Applications:

WB, IHC

Name of antibody:

PXN (Phospho-Tyr118)

Immunogen:

Synthetic peptide of human PXN (Phospho-Tyr118)

Full name:

paxillin (Phospho-Tyr118)

SwissProt:

P49023

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

65 kDa

WB Positive control:

NIH/3T3 cells untreated or treated with serum

WB Recommended dilution:

500-1000