Background:

This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X.

Applications:

ELISA, IHC

Name of antibody:

QTRT1

Immunogen:

Fusion protein of human QTRT1

Full name:

queuine tRNA-ribosyltransferase catalytic subunit 1

Synonyms:

TGT; TGUT; FP3235

SwissProt:

Q9BXR0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100