Background:

This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

RAB23

Immunogen:

Fusion protein of human RAB23

Full name:

RAB23, member RAS oncogene family

Synonyms:

HSPC137

SwissProt:

Q9ULC3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human tonsil

IHC Recommend dilution:

50-200