Background:

This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9.

Applications:

ELISA, WB, IHC

Name of antibody:

RAP1B

Immunogen:

Fusion protein of human RAP1B

Full name:

Ras-related protein Rap-1b

Synonyms：

K-REV, RAL1B

SwissProt:

P61224

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

21 kDa

WB Positive control:

HepG2 cells and Human cervical cancer tissue

WB Recommended dilution:

200-1000