Background:

The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2.

Applications:

ELISA, IHC

Name of antibody:

RBMS2

Immunogen:

Fusion protein of human RBMS2

Full name:

RNA binding motif single stranded interacting protein 2

Synonyms:

SCR3

SwissProt:

Q15434

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer;