Background:

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Applications:

ELISA, WB

Name of antibody:

REG1A

Immunogen:

Fusion protein of human REG1A

Full name:

regenerating family member 1 alpha

Synonyms:

P19; PSP; PTP; REG; ICRF; PSPS; PSPS1

SwissProt:

P05451

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

19 kDa

WB Positive control:

Human pancreas tissue lysate

WB Recommended dilution:

500-2000