Background:

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Applications:

ELISA, WB, IHC

Name of antibody:

REG1B

Immunogen:

Fusion protein of human REG1B

Full name:

regenerating family member 1 beta

Synonyms:

REGH; REGL; PSPS2; REGI-BETA

SwissProt:

P48304

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300

WB Predicted band size:

19 kDa

WB Positive control:

Human pancreas tissues lysates

WB Recommended dilution:

1000-5000