WB Recommended dilution:

500-1000

WB Positive control:

Mouse brain tissue lysates

WB Predicted band size:

60 kDa

SwissProt:

Q04206

Synonyms：

p65; NFKB3

Full name:

v-rel avian reticuloendotheliosis viral oncogene homolog A

Immunogen:

Peptide sequence around phosphorylation site of serine281(E-L-S(p)-E-P) derived from Human NF- kappaB .

Name of antibody:

RELA(Phospho-Ser281)

Applications:

WB

Back  ground:

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.