Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Applications:

WB

Name of antibody:

RELT

Immunogen:

Synthesized peptide derived from C-terminal of human TR19L.

Full name:

RELT tumor necrosis factor receptor

Synonyms：

TRLT; TNFRSF19L

SwissProt:

Q969Z4

WB Predicted band size:

46 kDa

WB Positive control:

Jurkat cells, COLO205 cells, 293 cells and HepG2 cells lysates

WB Recommended dilution:

500-3000