Background:

The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

RETREG1

Immunogen:

Fusion protein of human RETREG1

Full name:

reticulophagy regulator 1

Synonyms:

JK1; JK-1; FAM134B

SwissProt:

Q9H6L5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human thyroid cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

55 kDa

WB Positive control:

Human heart tissue lysate

WB Recommended dilution:

500-2000