Background:

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue.

Applications:

ELISA, WB

Name of antibody:

TMPRSS2

Immunogen:

Fusion protein of human TMPRSS2

Full name:

transmembrane protease, serine 2

Synonyms：

PP9284; PRSS10

SwissProt:

O15393

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

54 kDa

WB Positive control:

A549 cells

WB Recommended dilution:

200-1000