Background:

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Applications:

WB, IHC, IF

Name of antibody:

TNFAIP8

Immunogen:

Synthesized peptide derived from internal of human TFIP8.

Full name:

tumor necrosis factor, alpha-induced protein 8

Synonyms：

tumor necrosis factor, alpha-induced protein 8

SwissProt:

O95379

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

23 kDa

WB Positive control:

Huvec cells lysate

WB Recommended dilution:

500-3000

IF positive control:

A549 cells

IF Recommend dilution:

100-500