Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

Applications:

ELISA, WB

Name of antibody:

TNFRSF21

Immunogen:

Synthetic peptide of human TNFRSF21

Full name:

tumor necrosis factor receptor superfamily, member 21

Synonyms：

DR6, CD358, BM-018

SwissProt:

O75509

ELISA Recommended dilution:

1000-10000

WB Predicted band size:

72 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

500-2000