Background:

TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Applications:

ELISA, WB

Name of antibody:

TNIP3

Immunogen:

Synthetic peptide of human TNIP3

Full name:

TNFAIP3 interacting protein 3

Synonyms：

LIND; ABIN-3

SwissProt:

Q96KP6

ELISA Recommended dilution:

1000-2000

WB Predicted band size:

39 kDa

WB Positive control:

Mouse brain tissue

WB Recommended dilution:

200-1000