Background:

This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated.

Applications:

ELISA, WB, IHC

Name of antibody:

TNMD

Immunogen:

Synthetic peptide of human TNMD

Full name:

tenomodulin

Synonyms:

TEM; CHM1L; BRICD4

SwissProt:

Q9H2S6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

37 kDa

WB Positive control:

Human fetal liver tissue lysate

WB Recommended dilution:

500-2000