Background:

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.

Applications:

WB

Name of antibody:

TNNI3(Phospho-Ser43)

Immunogen:

Peptide sequence around phosphorylation site of Serine 43 (K-I-S(p)-A-S) derived from Human TNNI3.

Full name:

troponin I type 3 (cardiac)

Synonyms：

CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF

SwissProt:

P19429

WB Predicted band size:

24 kDa

WB Positive control:

Jurkat cells lysates

WB Recommended dilution:

500-1000