Background:

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Applications:

ELISA, WB

Name of antibody:

TNNT2

Immunogen:

Full length fusion protein

Full name:

troponin T2, cardiac type

Synonyms:

CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6

SwissProt:

P45379

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

36 kDa

WB Positive control:

Mouse heart tissue lysate

WB Recommended dilution:

200-1000