Background:

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms.

Applications:

WB

Name of antibody:

TP53(Phospho-Ser20)

Immunogen:

Peptide sequence around phosphorylation site of Serine 20 (T-F-S(p)-D-L) derived from Human p53.

Full name:

tumor protein p53

Synonyms：

P53; BCC7; LFS1; TRP53

SwissProt:

P04637

WB Predicted band size:

44 kDa

WB Positive control:

Mouse brain tissue lysates

WB Recommended dilution:

500-1000