Background:

TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

Applications:

ELISA, WB, IHC

Name of antibody:

TP53I11

Immunogen:

Synthetic peptide of human TP53I11

Full name:

tumor protein p53 inducible protein 11

Synonyms：

PIG11

SwissProt:

O14683

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

21 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

500-2000