Background:

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Applications:

ELISA, IHC

Name of antibody:

TPH1

Immunogen:

Fusion protein of human TPH1

Full name:

tryptophan hydroxylase 1

Synonyms：

TPRH; TRPH

SwissProt:

P17752

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human gastric cancer

IHC Recommend dilution:

15-50