Background:

TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.

Applications:

ELISA, WB

Name of antibody:

TPX2

Immunogen:

Fusion protein of human TPX2

Full name:

TPX2, microtubule-associated

Synonyms：

DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1

SwissProt:

Q9ULW0

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

86 kDa

WB Positive control:

K562 and A431 cells

WB Recommended dilution:

500-2000