Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Applications:

ELISA, IHC

Name of antibody:

MAPK11

Immunogen:

Synthetic peptide of human MAPK11

Full name:

mitogen-activated protein kinase 11

Synonyms：

P38B; SAPK2; p38-2; PRKM11; SAPK2B; p38Beta; P38BETA2

SwissProt:

Q15759

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human tonsil

IHC Recommend dilution:

25-100