Background:

MAPK15 (mitogen-activated protein kinase 15, ERK8) is a 544 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family (MAP kinase subfamily). MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPK15 functions as a catalytic kinase using ATP to produce ADP and a phosphoprotein. A TXY motif, containing one threonine and one tyrosine residue, activates the MAP kinases upon phosphorylation. MAPK15 is a ubiquitously expressed protein with highest expression found in lung and kidney.

Applications:

ELISA, IHC

Name of antibody:

MAPK15

Immunogen:

Fusion protein of human MAPK15

Full name:

mitogen-activated protein kinase 15

Synonyms：

ERK7; ERK8

SwissProt:

Q8TD08

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and human liver cancer

IHC Recommend dilution:

25-100