Background:

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Applications:

ELISA, IHC

Name of antibody:

MAPT

Immunogen:

Fusion protein of human MAPT

Full name:

microtubule-associated protein tau

Synonyms：

TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17

SwissProt:

P10636

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100