Background:

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired.

Applications:

WB

Name of antibody:

MBTPS1

Immunogen:

Synthesized peptide derived from C-terminal of human MBTPS1.

Full name:

membrane-bound transcription factor peptidase, site 1

Synonyms：

S1P; PCSK8; SKI-1

SwissProt:

Q14703

WB Predicted band size:

118 kDa

WB Positive control:

Jurkat and COLO205 lysates

WB Recommended dilution:

500-3000