概 述
Full name: |
keratin 17 |
Synonyms: |
PC; K17; PC2; 39.1; CK-17; PCHC1 |
Swissprot: |
Q04695 |
Gene Accession: |
BC000159 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. |